منابع مشابه
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Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. We aim to determine the sources of seizure-induced ROS and ...
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Spermatozoa are very special cells and constantly exposed to the interphase between oxidative stress through high amounts of reactive oxygen species (ROS) and leukocytes, and reduction by means of scavengers and antioxidants. Considering the very special functions of spermatozoa as being the only cells with such high polarization and exerting their functions outside the body, even in a differen...
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Reactive oxygen species (ROS) play key roles in many pathogenic processes, including carcinogenesis, inflammation, ischemia-reperfusion injury and signal transduction. Also, reactive nitrogen species (RNS) cause various biological events such as neurodegenerative disorders. Sensitive and specific detection methods for ROS and RNS in biological samples should be useful for elucidation of biologi...
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D ioxygen is a highly important, yet toxic, molecule that reacts in vivo to produce reactive oxygen species such as superoxide, peroxides, hydroxyl radicals, and other related species. Those species play important roles in healthy organisms, and they are implicated in aging and a wide range of disease processes as well. The contents of this Special Feature on Reactive Oxygen Species in Chemistr...
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A RANDOMIZED CLINICAL TRIAL by the Acute Respiratory Distress Syndrome Network (1) demonstrated a 22% reduction in mortality in patients by reducing the tidal volume for mechanical ventilation from the conventional setting of 12 ml/kg to a lower setting of 6 ml/kg. This dramatic decrease in mortality has stimulated significant interest in the mechanisms of ventilatorinduced lung injury and the ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2008
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.108.184325